Christopher Columbus embarked on his fourth and final journey into the New World.
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Five bank robbers armed themselves and attempted a heist in Norco, California.
President Barack Obama officially declared his support of same-sex marriage.
A steam locomotive called City of Truro became the first steam engine to go over 100 miles per hour.
The Luna 5 attempted to land on the Moon.
The Huffington Post was launched, founded by Arianna Huffington, Andrew Breitbart, Kenneth Lerer, and Jonah Peretti.