The first Native American uprising against Spanish rule occurred in the La Navidad colony.
Christopher Columbus discovered Puerto Rico on his second voyage.
Christopher Columbus discovered Sint Maarten in the West Indies.
Explorer Christopher Columbus, on his second voyage, found Dominica and the Kalinago people.
Explorer Christopher Columbus set sail on his second voyage with a larger fleet of 17 ships.
Pope Alexander VI divided the New World between Spain and Portugal.
Explorer Christopher Columbus wrote a letter about his travels to the New World.
Christopher Columbus left the New World to sail to Spain.
Christopher Columbus sighted manatees for the first time ever.